It is one of the termination of acute
inflammation . suppuration os molecular necrosis and liquefaction of tissues by
the pyogenic bacteria . The infected tissue will undergo necrosis and the dead
tissue will be liquefied by the leucocyte , bacteria and their ferments toi
form pus which is creasy or semisolid material . The pus is surrounded by
pyogenic membrane which is formed by thin layer of neutrophils lymphoytes , an
d few eosinophils . the formation of pus
will start after positive chemotaxis and necrosis of the tissue . When the
leucocyte mainly polymorphonuclear neutrophils , move towards the injurious agents and engulf agents. The
process is called phagocytes and this type of attracting property is called
positive chemotactic phenomenon . after necrosis , the necrosed tissue of skin
or mucous membrane may be thrown out , leading to ulcer . when the liquefied
material will be enclosed in the cavity below the surface , there will be formation of ab
scess . when there is massive necrosis , there may be formation of gangrene . Thus the suppuration will be
produced by –
i)
Necrosis of tissue
ii)
Sufficient leucocytes will come
in contact with injurious agents and engulf the injurious agents ( phagocytosis
) .
iii)
Digestion of dead material by proteolytic
ferment liberated by dead neutrophils and also bacterial ferments ..
